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Abstract #4285

Reproducibility of Cardiac 31P MRS at 7 T – Initial Results of a Multi-Center and Longitudinal Study

Stefan Wampl1, Ladislav Valkovic2, Ferenc Mozes2, Martin Meyerspeer1, and Albrecht Ingo Schmid1
1High Field MR Center, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, 2Oxford Centre for Clinical MR Research, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

Synopsis

Keywords: Heart, Spectroscopy, 31P MRSTo demonstrate reproducibility of cardiac 31P MR spectroscopy at 7T, three subjects were scanned on two sites in two different countries. The two sites are equipped with similar MR scanners but scanner platform versions, RF coil hardware and operators differed. The 16-channel receive array at site A provided 50% higher SNR than the 14cm single loop coil at site B, while site B achieved better linewidths, resulting in similar quality of spectral fitting. Two scan protocols were compared between the sites, both provided good reproducibility of cardiac PCr/ATP. This demonstrates the feasibility of larger multi-centre trials of cardiac MR spectroscopy.

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Keywords