Abstract #4287

The Effect of Resolution and Voxel Size on SNR for Cardiac Diffusion Tensor Imaging

Ariel J Hannum^1,2,3, Tyler E Cork^1,2,3, Kawin Setsompop^1,4, and Daniel B Ennis^1,2

¹Department of Radiology, Stanford University, Stanford, CA, United States, ²Division of Radiology, Veterans Administration Health Care System, Palo Alto, CA, United States, ³Department of Bioengineering, Stanford University, Stanford, CA, United States, ⁴Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Heart, Diffusion Tensor ImagingThe purpose of this work is to characterize how SNR varies with slice thickness for a given in-plane resolution for cDTI. We observed that noise in cDTI is largely physiological dominated such that increasing voxel volume yields smaller gains in SNR than what is observed in a phantom. More specifically, increased slice thickness did not significantly improve cDTI metric maps for a given in-plane resolution. However, higher in-plane resolution improved MD and FA maps. Therefore, future work will evaluate the optimal in-plane resolution and slice thickness.

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