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Abstract #4295

Characterization of Cardiac Quantitative Susceptibility Mapping (QSM)

Andrew Tyler1, Li Huang1, Radhouene Neji1,2, Ronald Mooiweer1,2, Pier-Giorgio Masci1, and Sébastien Roujol1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom

Synopsis

Keywords: Heart, SusceptibilityCardiac Quantitative Susceptibility Mapping (QSM) is a promising technique for the evaluation of iron levels in the myocardium, particularly after a hemorrhagic infarction. In this abstract, we validate the accuracy of our QSM acquisition and reconstruction procedure in phantom experiments, and characterize its precision and repeatability in the myocardium in a healthy volunteer cohort. We found a strong linear relationship between the gadolinium concentration and measured susceptibility in the phantom. In vivo QSM precision and repeatability in the myocardium were 0.11±0.05 ppm and 0.02±0.02 ppm, respectively.

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Keywords