Abstract #4302

Evaluating the myocardial fibre pattern in the equine heart using DTI: Protocol development for very a large ex-vivo sample

Lucy Elizabeth Kershaw¹, Rachel Jago², Jenny Reed², and John Keen²

¹Edinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom, ²The Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Synopsis

Keywords: Myocardium, Ex-Vivo ApplicationsWe aim to develop a protocol suitable for ex-vivo DTI of the equine heart. DTI on a large sample is challenging because this is already a low SNR technique. The main requirement for good-quality data in a formalin-fixed heart is to reduce TE as much as possible. The protocol recommendations presented here are largely common sense, but the long acquisitions required make troubleshooting extremely time consuming. We thought it important to share these findings for the benefit of other investigators

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