Keywords: Image Reconstruction, PhantomsIn this study, we introduced the parallel imaging technique GRAPPA to the flyback EPI with controlled aliasing in order to accelerate the acquisition time while simultaneously reducing artifacts. The GRAPPA-accelerated flyback EPI was characterized using MR phantoms with varying SNR and acceleration factor (R) and the feasibility of simultaneous bicarbonate and lactate imaging with the proposed scheme was also demonstrated. The proposed acquisition method has potential advantages for in vivo studies with hyperpolarized substrates by shortening acquisition time, improving spatial resolution, and increasing effective flip angles.
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