Keywords: Cartilage, JointsThe aim of this work was to identify focal changes in T2 relaxation times inside and outside regions of tibiofemoral contact in loaded cadaver knee articular cartilage whole, superficial, and deep layers. We used a cluster analysis approach to identify regions of change in T2 relaxation time. We found that 1) decreases in T2 relaxation time with load appeared predominantly inside of the femoral and tibial cartilage contact areas, and 2) greater decreases in T2 within the tibial and femoral cartilage contact area were observed in the superficial layer of cartilage.
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