Abstract #4365

Comparing the effect of body weight, BMI and physical activity intensity on calcified and uncalcified cartilage using quantitative UTE MRI

Hanqi Wang¹, Qing Li², Stefan Sommer^3,4,5, and Yong Lu¹

¹Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, ²MR Collaborations, Siemens Healthineers Ltd., Shanghai, China, Shanghai, China, ³Siemens Healthineers International AG, Zurich, Switzerland, Zurich, Switzerland, ⁴Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland, Zurich, Switzerland, ⁵Advanced Clinical Imaging Technology (ACIT), Siemens Healthineers International AG, Lausanne, Switzerland, Lausanne, Switzerland

Synopsis

Keywords: Cartilage, CartilageUTE technique was utilized to quantitatively assess calcified cartilage (CC) and uncalcified cartilage (UC). T2* values of UC in patella, medial tibia and lateral femur positively moderately correlated with body weight, while T2* values of CC showed no significant correlation. T2* values of UC showed no significant correlation with BMI, while T2* values of CC in medial femur and lateral tibia showed negatively strong and positively moderate correlation, respectively. T2* values of CC and UC showed no significant correlation with physical activity level. The mechanical loading effect performs different between CC and UC, indicating their different bio-mechanical properties.

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