Abstract #4372

T2 and T1rho mapping of equine metacarpophalangeal joint cartilage

Carly Lockard¹, Brad Sutton², Bruce Damon¹, Xiaojuan Li³, and Annette McCoy⁴

¹Stephens Family Clinical Research Institute, Carle Clinical Imaging Research Program, Carle Health, Urbana, IL, United States, ²The Grainger College of Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States, ⁴Department of Veterinary Clinical Medicine (College of Veterinary Medicine), University of Illinois, Urbana, IL, United States

Synopsis

Keywords: Cartilage, Quantitative ImagingHorses are an excellent translational model of orthopedic disease with high relevance to human disease. T2 and T1rho mapping can provide information about early cartilage changes in a horse post-traumatic osteoarthritis model. We investigated the feasibility of using MAPSS-based T2 and T1rho mapping in the horse metacarpophalangeal joint cartilage in cadaver specimens and live horses with and without joint pathology. MAPSS-based T2 and T1rho mapping of equine metacarpophalangeal joint cartilage is feasible and provides realistic cartilage relaxometry values.

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