Abstract #4373

Evaluating the relationship of proximal femoral bone shape asymmetry with cartilage health and biomechanics in patients with hip OA

Rafeek Thahakoya¹, Valentina Pedoia¹, Kenneth Gao¹, Rupsa Bhattacharjee¹, Felix Gassert¹, Johanna Luitjens¹, Koren Roach¹, Eric Hammond¹, Richard Souza^1,2, and Sharmila Majumdar¹

¹Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ²Department of Physical Therapy and Rehabilitation Science, University of California San Francisco, San Francisco, CA, United States

Synopsis

Keywords: Bone, OsteoarthritisThis current study evaluated the role of bone shape asymmetry with other biomarkers of hip OA such as T1rho/T2 relaxation time and gait biomechanics data. We observed similar relationship trend in higher bone asymmetry values in the AMS region correlates with lesser number of repetitions performed 30s chair rise test, validating the common understanding of performance. This is one of the first feasibility studies to be explored which conveys the potential of bone asymmetry to be considered as a strong biomarker for understanding hip OA

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