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Abstract #4449

The value of amide proton weighted imaging in predicting perineural invasion of prostate cancer

Xiwei Li1, Lihua Chen1, Nan Wang1, Jiazheng Wang2, and Ailian Liu1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare,Beijing, Beijing, China

Synopsis

Keywords: Prostate, CancerPerinerval infiltration (PNI) is closely related to the degree of radical operation and postoperative recurrence. Pathological examination is the gold standard for PNI diagnosis, but it is an invasive examination. The APTw imaging can be used for disease diagnosis and therapeutic evaluation by detecting the content of protein and polypeptide in tissues and cells. In this study, APTw was used to evaluate the PNI in prostate cancer. The results showed that the APT values of PNI (+) group was higher than other one group. Therefore, APTw is of great value in differentiation of perinerval invasion from prostate cancer.

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