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Abstract #4450

ADC histogram features of rectal cancer before and after neoadjuvant radiation to predict heterochronic hematogenous metastasis

Xiaoxian Zhang1, Chunmiao Xu1, Zhiwei Shen2, Ke Jiang2, and Xuejun Chen1
1Henan tumor hospital, Zhengzhou, China, 2Philips healthcare,Beijing,China, Beijing, China

Synopsis

Keywords: Cancer, Diffusion/other diffusion imaging techniquesBloodstream metastasis to the liver, lung, and bone is the most prevalent mechanism of rectal cancer metastasis. However, there are currently no good indications for diagnosing heterochronic hematogenous metastases at the early stage. Therefore, this study aimed to explore whether ADC histograms might predict new heterochronic hematogenous metastases before and after neoadjuvant radiation for rectal cancer. Results showed that the first-order histogram feature ADC5% derived from post-treatment ADC maps might be utilized as an imaging biomarker and an independent predictor of new heterochronic hematogenous metastases after surgery following neoadjuvant chemotherapy for rectal cancer.

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Keywords