Keywords: Screening, Quantitative Imaging, MR body composition analysis, phenotyping, subcutaneous fat, resting state fMRIPhenotyping individuals are gaining importance in personalized medicine. This MR based body composition analysis and resting state (R-fMRI) along with autonomic functions (AFT) evaluation have determined parameters for physical, functional and physiological phenotyping in healthy volunteers (n=30). MR studies (at 3T) were R-fMRI using EPI sequence, subcutaneous fat evaluation by mDIXON sequence and AFT included parasympathetic (deep breathing, HUT) and sympathetic (HUT, hand grip test, cold pressor test). Increased functional activation, higher abdominal fat and fall in Baroreflex independent sympathetic reactivity were observed in volunteers having BMI ≥25 Kg/m2 compared to those with BMI <25Kg/m2.
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