Keywords: Heart, Radiomics, ReproducibilityRadiomics has been applied in cardiovascular imaging with promising results. Still, the effect of imaging parameters on the reproducibility of radiomics features needs to be well understood for these to be used in clinical diagnostics. We conduct a retrospective study on short-axis cine CMR images of healthy volunteers to assess the impact of different temporal sampling parameters on the reproducibility of shape, first-order, texture, and deformation field-based features, and contextualize the findings with inter- and intra-observer variability. We find that the reproducibility of features is dependent on temporal sampling, warranting the introduction of parameter standardization for radiomics analyses.
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