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Abstract #4464

Impact of mitral valve repair on left atrial fibrosis in severe mitral valve regurgitation patients: a 3D LGE pilot follow-up study.

Sulayman el Mathari1, Jolanda Kluin1, Luuk Hopman2, Pranav Bhagirath2, Maurice Oudeman1, Alexander Vonk1, Steven Chamuleau2, Robert Klautz1,3, Aart Nederveen4, Pim van Ooij4, and Marco Götte2
1Cardiothoracic Surgery, AmsterdamUMC, Amsterdam, Netherlands, 2Cardiology, AmsterdamUMC, Amsterdam, Netherlands, 3Cardiothoracic Surgery, LUMC, Leiden, Netherlands, 4Radiology and Nuclear Medicine, AmsterdamUMC, Amsterdam, Netherlands

Synopsis

Keywords: Valves, Valves, FibrosisTiming of mitral valve repair (MVR) surgery in mitral valve regurgitation (MR) patients remains a subject of debate. Assessment of left atrial (LA) fibrosis might aid to improve clinical management of these patients. We assessed LA fibrosis extent using 3-dimensional late gadolinium enhanced cardiac magnetic resonance imaging prior to and after MVR surgery in MR patients (n=6). Our data demonstrates a decrease of LA volume, while a concomitant increase in LA fibrosis was observed. Further study is required to determine the potential relation between LA fibrosis, pre- and post-operative changes and long-term clinical outcome.

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