Keywords: Microstructure, Microstructure
We present a new Monte Carlo MR simulator, which in addition to simulating the random diffusion of water restricted by any obstacles also simulates (1) the off-resonance field due to myelin and (2) signal loss due to magnetisation transfer. We use this simulator to study the interaction of diffusion, relaxation, and magnetisation transfer. We simulate gradient and spin echo measurements in white matter. The myelin off-resonance field is found to greatly reduce T2* due to dephasing of the signal between compartments, but barely affects T2. Magnetisation transfer at tissue boundaries explains T2 differences between intra-, extra-axonal, and myelin water.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords