Abstract #4506

Batch-mode production of hyperpolarised xenon gas with a continuous-flow polariser for preclinical and clinical human lung ventilation images

Michael Vaeggemose^1,2, Graham Norquay ³, Esben Søvsø Szocska Hansen¹, Neil J. Stewart³, Oliver I. Rodgers³, Ryan S. Munro³, Rolf F. Schulte⁴, Guilhem J. Collier ³, Christoffer Laustsen¹, and Jim M. Wild³

¹MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark, ²GE Healthcare, Brøndby, Denmark, ³POLARIS group, University of Sheffield, Sheffield, United Kingdom, ⁴GE Healthcare, Munich, Germany

Synopsis

Keywords: Hyperpolarized MR (Gas), Hyperpolarized MR (Gas), Lung ventilation imaging

Hyperpolarised ¹²⁹Xe gas was accumulated using spin-exchange optical pumping (SEOP) by continuous-flow of xenon gas directly from the cell without the use of cryogenic separation. 3D ventilation images were acquired in human and porcine models to determine clinical diagnostic image quality. Xenon ventilation image quality indicates that on demand batch production of xenon is feasible for both preclinical and clinical lung ventilation imaging examinations.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.