Abstract #4525

Assessment of vertebral and intervertebral disc microenvironment changes in postmenopausal women using IVIM and fat-water MRI

Shuo Zhang¹, Qingwei Song¹, Hongbo Feng¹, Qianrui Guo², and Yang Yang³

¹The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Dalian Medical University, Dalian, China, ³Beijing United Imaging Research Institute of Intelligent Imaging, Beijing, China

Synopsis

Keywords: Bone, Data AcquisitionIntravoxel incoherent motion (IVIM) and fat-water magnetic resonance imaging (FWMRI) are rarely used for vertebral and intervertebral disc. To search for predictive value of them in assessing the lumbar spine microenvironment changes, we performed a study with postmenopausal women combined the parameters with bone mineral density (BMD) and major fracture risk assessment (FRAX) score. We report that fat fraction (FF) has significant correlation with FRAX, FF was moderately negatively correlated with BMD; ADC_slow of intervertebral discs showed moderately negatively correlation with FRAX score and FF. IVIM and FWMRI have potential to become new biomarkers in predicting lumbar spine microenvironment changes.

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