Keywords: Bone, Quantitative Imaging, Multiecho Dixon Technique , IVIM-DWIBone mineral density (BMD) is a common standard for evaluating osteoporosis, but it can only reflect the change of bone mass, not the microscopic nodules of tissueChange of structure.Multi-echo Dixon and IVIM-DWI were used to evaluate the changes of spinal bone marrow microstructure in osteoporosis, osteopenia and normal subjects.The results showed that there were significant differences in FF, D and D* between osteoporosis, osteopenia and normal subjects.These results indicate that IVIM-DWI can quantitatively reflect the changes of lumbar microcirculation and fat content, and can be used as a biomarker for the progression of osteoporosis.
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