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Abstract #4531

Toward an Imaging Biomarker for Proximal Femur Fracture Risk Using 3T Chemical Shift-Encoded MRI Radiomic Of Bone Marrow

Dimitri Martel1, Benjamin Leporq2, Anmol Monga1, Stephen Honig3, and Gregory Chang1
1Radiology, NYU Langone, New York, NY, United States, 2Université de Lyon; CREATIS CNRS UMR 5220, Inserm U1206, INSA-Lyon, Villeurbanne, France, 3Osteoporosis Center, Hospital for Joint Diseases, NYU Langone, New York, NY, United States

Synopsis

Keywords: Bone, RadiomicsRecent studies using Chemical Shift Encoded-MRI have used textural analysis to assess vertebral marrow heterogeneities in postmenopausal women and in paraspinal muscle to predict its strength. Radiomics provide another means to quantify bone marrow on MR images, specifically by analyzing texture, shape, and intensity distribution in the region of interest. Our aim was to investigate whether radiomic features in fatty acid composition maps of the proximal femur bone marrow improve the prediction of osteoporotic fracture.

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