Abstract #4540

Ultrashort Echo Time, MRI porosity index, and suppression ratio correlate with the cortical bone microstructural and mechanical properties

Saeed Jerban ^1,2,3, Yajun Ma^1,2, Salem Alenezi ⁴, Dina Moazamian¹, Jiyo Athertya¹, Hyungseok Jang^1,2, Erik Dorthe⁵, Darryl Dlima⁵, Gina Woods⁶, Christine B Chung^1,2, Eric Y Chang^1,2, and Jiang Du^1,2

¹Department of Radiology, University of California, San Diego, La Jolla, CA, USA, San Diego, CA, United States, ²Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, CA, USA, San Diego, CA, United States, ³Department of Orthopedic Surgery, University of California, San Diego, La Jolla, CA, USA, San Diego, CA, United States, ⁴Research and Laboratories Sector, Saudi Food and Drug Authority, Riyadh, KSA, Riyadh, Saudi Arabia, ⁵Shiley Center for Orthopedic Research and Education at Scripps Clinic, La Jolla, CA, USA, San Diego, CA, United States, ⁶Department of Medicine, University of California, San Diego, La Jolla, CA, USA, San Diego, CA, United States

Synopsis

Keywords: Bone, BoneThe cortical bone porous microstructure can be evaluated using ultrashort echo time (UTE) MRI. UTE-MRI-based evaluation of bone has been underutilized partly due to the high cost and time demands of MRI in general. The porosity index (PI) and the suppression ratio (SR) are two rapid UTE-based bone evaluation techniques (~ 5 mins scan time each), which can potentially reduce the time demand and cost in future clinical studies. We have investigated the relationship of PI and SR measures with human cortical bone microstructural and mechanical properties. PI and SR showed significant correlations with microstructural and mechanical properties.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.