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Abstract #4562

RF pulse optimization for robust excitation in 31P magnetization transfer spectroscopy

Christina Graf1, Clemens Diwoky2, Armin Rund3, and Rudolf Stollberger1
1Institute of Biomedical Imaging, Graz University of Technology, Graz, Austria, 2Institute of Molecular Biosciences, Karl-Franzens University Graz, Graz, Austria, 3Institute for Mathematics and Scientific Computing, Karl-Franzens University Graz, Graz, Austria

Synopsis

Keywords: RF Pulse Design & Fields, RF Pulse Design & FieldsIn this work, robust excitation pulses for 31P spectroscopy at 7T are designed by optimal control. The particular challenges of inhomogeneous RF field due to use of surface RF coils and broad bandwidth requirements due to the nature of 31P were addressed thoroughly. The optimized RF pulses show superior performance compared to adiabatic RF pulses during numerical simulations and phantom experiments. Application of the optimized RF pulses to T1 prediction by dual angle method is the logical consequence.

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