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Abstract #4590

Reproducibility and variability of tailored and universal nonselective excitation pulses at 7T for human body imaging: Re-scans after one year

Christoph Stefan Aigner1, Jean Pierre Bassenge1,2, Sebastian Dietrich1, Max Lutz1, Felix Krüger1, and Sebastian Schmitter1,3,4
1Physikalisch-Technische Bundesanstalt (PTB), Berlin and Braunschweig, Germany, 2Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine, Berlin, Germany, 3Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 4University of Minnesota, Center for Magnetic Resonance Research, Minneapolis, MN, United States

Synopsis

Keywords: RF Pulse Design & Fields, Parallel Transmit & Multiband3D ultrahigh field (UHF) imaging of the body, particularly the heart, is highly challenging due to the inhomogeneous transmit field (B1+) leading to spatially varying flip-angle (FA) patterns. This study demonstrates that pre-computed universal pulses (UPs) allow for calibration-free 3D cardiac FA homogenization at 7T, despite inter-subject variations because of sex, age, BMI, and coil-placement differences. Furthermore, the performance is robust across multiple MRI operators or re-scans after one year. UPs are, therefore, suited to significantly simplify UHF cardiac imaging by removing the need for lengthy calibration prescans.

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