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Abstract #4614

Differential quantification of cortical and medullary perfusion through Gaussian Mixture Model based segmentation on transplanted renal MRI

Anne Oyarzun-Domeño1,2, Izaskun Cía 1, Rebeca Echeverria-Chasco2,3, María A. Fernández-Seara2,3, Paloma L. Martin-Moreno2,4, Nuria Garcia-Fernandez2,4, Gorka Bastarrika2,3, Javier Navallas1,2, and Arantxa Villanueva1,2,5
1Electrical, Electronics and Communications Engineering, Public University of Navarre, Pamplona, Spain, 2Health Research Insitute of Navarra, IdiSNA, Pamplona, Spain, 3Department of Radiology, Clínica Universidad de Navarra, Pamplona, Spain, 4Department of Nephrology, Clínica Universidad de Navarra, Pamplona, Spain, 5Institute of Smart Cities (ISC), Pamplona, Spain

Synopsis

Keywords: Data Processing, PerfusionRenal perfusion quantification is of importance in the post-operative surveillance of the allograft in translated patients. Together with cortical perfusion measurement, there is a strong interest in the quantification of medullary perfusion values, which requires an additional segmentation step of renal compartments. We applied Gaussian Mixture Models over renal MRI dataset to automatically extract the labels for each compartment to separately calculate cortical and medullary perfusion values. Proposed method showed performance metrics above 85% against ground truth labels and correlation coefficient above 96% and 58% for cortical and medullary perfusion values comparing with ground truth perfusion values.

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Keywords