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Abstract #4651

Accelerated Four-Dimensional Rosette J-resolved Spectroscopic Imaging (4D ROSE-JRESI) with semi-LASER Localization: A pilot study

Ajin Joy1, Uzay Emir2,3, Paul M. Macey4, and M. Albert Thomas1
1Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2School of Health Sciences, Purdue University, West Lafayette, IN, United States, 3Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States, 4School of Nursing and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, United States

Synopsis

Keywords: Data Acquisition, BrainUndersampling spatial and spectral dimensions is essential to achieve clinically feasible scan times in multi-dimensional spectroscopic imaging. Sampling pattern of rosette trajectory has higher incoherence than that of the other non-Cartesian trajectories like spiral and radial, and can achieve higher compressed-sensing reconstruction performance. While rosette spectroscopic imaging has been attempted for 2D (2 spatial+1 spectral) and 3D (3 spatial+1 spectral) spectroscopic imaging, it has thus far not been shown for J-resolved spectroscopic imaging. In this pilot study, we implemented a rosette echo-planar J-resolved spectroscopic imaging (ROSE-JRESI) sequence and studied the feasibility of high acceleration factors for clinically feasible runtimes.

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Keywords