Abstract #4656

Spiral-GRASP-UTE: 4D Real-Time MRI of the Lung with Sub-Second Temporal Resolution

Ding Xia¹, Ye Tian², Thomas Benkert³, and Li Feng¹

¹Biomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States, ³MR Applications Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: Lung, LungThe purpose of this work was to develop a dynamic lung MRI framework, called Spiral-GRASP-UTE, for 4D real-time imaging of the lung with sub-second temporal resolution. Spiral-GRASP-UTE combines continuous ultra-short echo time (UTE) variable-density stack-of-spirals acquisition with a recently developed GRASP-Pro reconstruction technique that is based on a low-rank subspace model. Compared to other state-of-the-art lung MRI methods using 3D radial Kooshball sampling, Spiral-GRASP-UTE enables fast free-breathing dynamic lung imaging (2-3 minutes) and a high temporal resolution of less than one second per volume. This eliminates the need for respiratory motion detection and compensation, which is often challenging in lung MRI.

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