Abstract #4670

Assessment of pulmonary function in pulmonary embolism using phase-resolved functional pulmonary MRI (PREFUL-MRI) under free breathing

Tao Ouyang¹, Yichen Tang¹, Chen Zhang², Jens Vogel-Claussen³, Andreas Voskrebenzev³, Xiuqin Jia¹, and Qi Yang¹

¹Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China, ²MR Scientific Marketing, Siemens Healthcare, Beijing, China, ³Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany

Synopsis

Keywords: Lung, PerfusionThis study investigated the difference in pulmonary function (including perfusion and ventilation defects) using PREFUL-MRI between pulmonary embolism patients and healthy volunteers. Three coronal slices were acquisitor with MAGNETOM Prisma 3T MR scanner per subject. The results showed that perfusion and ventilation defect percentages derived from PREFUL-MRI in PE patients were higher than in healthy subjects. And the PREFUL-MRI parameters showed a strong correlation with spirometry parameters in PE patients. Our study suggests that PREFUL-MRI allows for the quantification of lung function under free breathing and non-contrast in PE patients, making this a promising tool for future monitoring of patients

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