Meeting Banner
Abstract #4674

Same-day Comparison of 129Xe MRI Ventilation Across Two MRI Manufacturers

Rachel L Eddy1,2,3, Vanessa M Diamond2, Girija Bhatnagar2, Alexandra Schmidt1, Jonathon A Leipsic1,4, Don D Sin1,3, Bradley S Quon1,3, and Jonathan H Rayment2,5
1Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada, 2BC Children's Hospital Research Institute, Vancouver, BC, Canada, 3Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 4Department of Radiology, University of British Columbia, Vancouver, BC, Canada, 5Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada

Synopsis

Keywords: Lung, Hyperpolarized MR (Gas)Hyperpolarized 129Xe gas MRI (XeMRI) is gaining traction globally as a primary endpoint in clinical trials, however it is unknown how images and measurements directly compare across different MRI scanner platforms. Here we compared same-day ventilation XeMRI across two MRI manufacturers at two sites in Vancouver Canada in patients with cystic fibrosis and healthy controls, to determine the interoperability across MRI platforms. Between-site ventilation images showed strong spatial overlap, and quantitative ventilation defect percent measurements showed strong agreement across all participants. These results support the use of XeMRI in multi-center studies irrespective of MRI platform.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords