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Abstract #4681

Differences in Myocardial Strain at End-Inspiration versus End-Expiration with Remote Exposure to Secondhand Tobacco Smoke

Huiming Dong1, Ang Zhou1, Natalie Au2, Mehrdad Arjomandi2, and Dimitrios Mitsouras1
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Divisions of Pulmonary, Critical Care, Allergy, and Sleep Medicine and Occupational and Environmental Medicine, University of California, San Francisco, San Francisco, CA, United States

Synopsis

Keywords: Myocardium, Myocardium, Cardiopulmonary; Second-Hand SmokerProlonged exposure to secondhand tobacco smoke (SHS) is associated with abnormal pulmonary function and cardiovascular response. In this study, we examined cardiac function in SHS-exposed participants using cardiac MR (CMR) and displacement encoding with stimulated echoes (DENSE) to determine whether the cardiac function is affected by air trapping-a hallmark of heavy past SHS exposure. We found that SHS-exposed participants had lower myocardial radial strain than unexposed participants at both end-inspiration and end-expiration imaging. Neither stroke volume nor cardiac output exhibited the decrease seen in unexposed participants at end-inspiration, but radial strain was significantly lower compared to end-expiration in SHS-exposed participants.

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