Abstract #4684

Diagnostic value of myocardial strain for evaluating pig model in ischemia with non-obstructive coronary artery disease

Zilong Ren¹, Didi Wen², Jianxiu Lian³, Jiantao Liu³, Zhe Huang³, and Minwen Zheng⁴

¹Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China, ²Department of Radiology, Xijing Hospital, Forth Military Medical University, Xi'an, China, ³Philips Healthcare China, Xi'an, China, ⁴Xijing Hospital, Fourth Military Medical University, Xi'an, China

Synopsis

Keywords: Myocardium, AnimalsTo explore whether myocardial strain can predict functional changes for ischemia with non-obstructive coronary artery disease (INOCA) in animal models. Results showed pigs with INOCA had lower global circumferential strain (GCS) and global longitudinal strain (GLS) (mean GCSnormal = -20.2 ± 2.0 %, mean GCSINOCA = -16.6 ± 1.4 %, P = 0.009; mean GLSnormal = -19.6 ± 1.9 %, mean GLSINOCA = -14.5 ± 3.0 %, P = 0.027). Therefore, the results showed that the myocardial deformation decreased in pigs with INOCA, which could provide information for the therapy of INOCA patients.

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