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Abstract #4690

Cardiovascular MRI combined with catheterization for objective assessment of cardiac function: data- and model-derived pressure-volume loops

Maria Gusseva1,2,3, Daniel A. Castellanos4, Tarique Hussain1, Dominique Chapelle2,3, and Radomír Chabiniok1,2,3,5
1Department of Paediatrics, UT Southwestern Medical Center, Dallas, TX, United States, 2Inria, Palaiseau, France, 3Ecole Polytechnique, Palaiseau, France, 4Department of Cardiology, Boston Children’s Hospital, Boston, MA, United States, 5Czech Technical University in Prague, Prague, Czech Republic

Synopsis

Keywords: Heart, ModellingClinical pressure-volume data are often subjected to measurement noise. In the present work we explore the potential of a biomechanical model of the heart as a data-filtering tool. We use cardiovascular MRI volume data either simultaneously or sequentially acquired with catherization. We use time-varying elastance metrics for a quantitative comparison of data- and model-derived pressure-volume loops (PV loops). Our results demonstrate that the biomechanical model provides high quality PV loops that could be used to replace noisy data signals. In addition, this work contributes to the increased understanding of cardiovascular MRI results.

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