Meeting Banner
Abstract #4702

Full cardiac cycle coverage T2* mapping detects early myocardial changes in hypertrophic cardiomyopathy

Oumaima Laghzali1,2, Sandra Lehmann1,3, Joao dos Santos Periquito1, Andreas Pohlmann1, Lucie Carrier4,5, Thoralf Niendorf1,2,6, Sonia Waiczies1, and Min-Chi Ku1,2
1Berlin Ultrahigh Field Facility (B.U.F.F), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, 2DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany, 3Technische Universität Berlin, Berlin, Germany, 4Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 5DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany, 6Experimental and Clinical Research Center, Charite Medical Faculty and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

Synopsis

Keywords: Cardiomyopathy, Tissue Characterization, Tissue remodeling

Most cases of hypertrophic cardiomyopathy (HCM) are detected at a stage when the heart has experienced significant damage. The aim of this study is to detect subtle changes in the myocardium before the appearance of overt symptoms of HCM. We show that myocardial T2* mapping can detect early changes throughout the full heart cycle in a HCM mouse model that represents the human genetic heart disease. This could potentially provide a biomarker for early stages of HCM that might be useful for non-invasive diagnoses.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords