Abstract #4730

Reproducibility of 7T human cardiac 3D 31P-MRSI using concentric ring k-space trajectories (CRT).

Ferenc E Mózes¹, William T Clarke², and Ladislav Valkovič^1,3

¹Oxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom, ²Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, ³Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia

Synopsis

Keywords: Non-Proton, Heart, phosphorusCardiac 31P-MRS provides insight into metabolism of the failing heart. The commonly employed 3D-MRSI acquisitions are rather slow, even at 7T. Fast readout trajectories, such as concentric ring (CRT) have been recently suggested to substitute the slow Cartesian sampling (CSI), however their repeatability is yet unknown. Our preliminary data suggest comparable intra-session repeatability, but somewhat lower inter-session repeatability for mid septal voxels using 2.5 min CRT in comparison to 6.5 min CSI. Similar trends were observed for higher resolution CRT.

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