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Abstract #4731

Analysis of regional differences in pH values obtained via 31P MRSI at 7T

Justyna Platek1,2, Florian Kroh1,2, Vanessa L. Franke1,2, Philip S. Boyd1, Nina Weckesser3, Heinz-Peter Schlemmer3,4, Daniel Paech3,5, Mark E. Ladd1,2,4, Peter Bachert1,2, and Andreas Korzowski1
1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidleberg, Germany, 2Faculty of Physics and Astronomy, University of Heidelberg, Heidelberg, Germany, 3Division of Radiology, German Cancer Research Center (DKFZ), Heidleberg, Germany, 4Faculty of Medicine, University of Heidelberg, Heidelberg, Germany, 5Division of Neuroradiology, University Hospital Bonn, Bonn, Germany

Synopsis

Keywords: Non-Proton, Spectroscopy, Phosphorus, pH, cancerIn this study, we analyzed pH values obtained via high-resolution 31P MRSI at 7T in different subjects and different regions of the human brain, and identified a trend towards lower pH values in the frontal region compared to other brain regions. The potential regional variation should be taken into account in cases, where only small pH changes between different tissues are expected and partial volume effects might dominate.

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Abstract Presentation Video

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