Keywords: Psychiatric Disorders, Brain, Minimal hepatic encephalopathy cognitionArtificial liver support is an increasingly important intermediate step in the treatment of patients with liver failure. Yet there is still a lack of imaging studies to evaluate the efficacy of artificial liver support (especially on cognitive function of MHE). This study sought to evaluate the temporal variability of ReHo in the brain spontaneous activity after artificial liver support and correlated it with the PHES.We found that the dReHo in the right superior frontal gyrus decreased and were negatively correlated with NCT-A and positively correlated with DST.Dynamic regional indexes might be a novel neuro-imaging biomarker for artificial liver efficacy evaluation.
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