Abstract #4795

Full-brain multi-pathway relaxometry using a golden-angle radial scheme and sparsely-sampled radial spokes

Li-Ya Shao¹, Zih-Ci Wang², Bruno Madore³, and Cheng-Chieh Cheng²

¹Department of Electrical Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ²Department of Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ³Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Data Acquisition, RelaxometryQuantitative MRI is emerging as a powerful diagnostic tool for neuroimaging applications. A motion-robust, golden-angle radial acquisition version of the ‘triple-echo steady-state’ (TESS) relaxometry method was implemented here, to mitigate the artifacts induced by the flowing motion of the cerebrospinal fluid (CSF). To improve the scan efficiency, a probability density function-based sparse sampling scheme was introduced in each radial spoke. Close agreement was obtained between reference and TESS scans for both T₁ and T₂ values, using a multi-compartment phantom. In vivo whole-brain results were further obtained (3D T₁ and T₂ maps, 1-mm isotropic resolution, whole-brain coverage, 7.5-minute scan).

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