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Abstract #4799

A Physics-informed Conditional Wasserstein Autoencoder to Quantify Uncertainties in Accelerated 2D Dynamic Radial MRI

Sherine Brahma1, Tobias Schaeffter1,2,3, Christoph Kolbitsch1,3, and Andreas Kofler1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2Department of Biomedical Engineering, Technical University of Berlin, Berlin, Germany, 3School of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom

Synopsis

Keywords: Image Reconstruction, Cardiovascular, Radial AcquisitionUncertainty quantification (UQ) can provide important information about deep learning algorithms and help interpret the obtained results. UQ for multi-coil dynamic MRI is challenging due to the large scale of the problem and scarce training data. We approach these issues by learning distributions in a lower dimensional latent space using a conditional Wasserstein autoencoder while utilizing the MR data acquisition model and by exploiting spatio-temporal correlations of the cine MR images. Our results indicate excellent image quality accompanied with uncertainty maps that correlate well with estimation errors.

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Keywords