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Abstract #4839

Do myocardial balanced steady-state free precession signal intensity curves allow to distinguish infarct patients from healthy subjects?

Tom Dresselaers1,2, Baptiste Vande Berg1, Sofie Tilborghs3,4, Alexandru Cernicanu5, and Jan Bogaert1,2
1Radiology, UZ Leuven, Leuven, Belgium, 2Dept. of Imaging and Pathology, KU Leuven, Leuven, Belgium, 3Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium, 4Medical Imaging Research Center, UZ Leuven, Leuven, Belgium, 5Philips Benelux, Eindhoven, Netherlands

Synopsis

Keywords: Myocardium, Cardiomyopathy, infarctionPre-contrast balanced steady-state free precession (bssfp) cine images seem to contain sufficient information to identify patients with an acute or chronic myocardial infarction using radiomics or deep learning methods. The reason remains however to be elucidated. It is also unclear if the cardiac phase should be considered although radiomics features vary through the heart cycle. In this study we show that the known global myocardial bssfp signal intensity variations observed in healthy subject are in fact segment dependent and have a reproducible three peak profile. In patients with acute myocardial infarct these profiles shows segment dependent alterations vs. controls.

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