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Abstract #4842

New Tagging MRI Method is More Sensitive than Ejection Fraction for Assessment of Contractile Function Recovery in Infarcted Pig Hearts

Anna V Naumova1 and William S Kerwin1
1Radiology, University of Washington, Seattle, WA, United States

Synopsis

Keywords: Myocardium, Heart, myocardial infarctionA new tagging method has been proved as a sensitive approach for assessment of regional deformation in the infarcted pig’s heart. The linear tags were placed in 60-degree pattern offsets and aligned with the AHA segments. The tagging analysis algorithm uses local Fourier transformation of the isolated spectral peaks. We have shown the temporal changes in circumferential strain of the infarcted segments of myocardium and faster recovery of myocardial strain followed by 60-min ischemia-reperfusion injury in comparison with 90-min. Circumferential strain was a more sensitive parameter for earlier detection of regional contractile dysfunction in comparison with ejection fraction.

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Keywords