Meeting Banner
Abstract #4844

Tracking lipid and macromolecular changes in Ex-vivo hearts using NOEMTR and rNOE at 7T

Blake Benyard1, Sophia Swago 1, Neil E. Wilson1, Paul S. Jacobs1, Walter Witschey1, Mohammed Harris1, and Ravinder Reddy1
1Center for Advanced Metabolic Imaging in Precision Medicine (CAMIPM), Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Keywords: Myocardium, Heart, CEST & MTTwo ex-vivo animal hearts were scanned at 7T to track lipid and macromolecular changes using NOEMTR and rNOE. Data was acquired on a fresh lamb heart and a healthy Yorkshire swine with an anteroseptal infarct by occlusion of the left anterior descending (LAD) coronary artery. After performing a multi-pool analysis, it is demonstrated that the NOEMTR and rNOE signal decreases in the infarcted region of the swine heart compared to the normal tissue and lamb heart.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords