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Abstract #4845

Vasodilator Stress Myocardial Strain in Coronary Artery Disease:An Animal Study With Histological Validation

Jing Xu1, Zhao Shihua1, and Minjie Lu1
1Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital, Beijing, China

Synopsis

Keywords: Myocardium, HeartATP can cause a pronounced positive inotropic effect on human heart. CMR-FT even at rest provides an excellent negative predictive value for myocardial ischemia and infarction in patients with CAD. CMR-FT is easy to perform without the need for dedicated acquisition and complex post-processing which can be applied to standard CMR cine sequences. Rest myocardial strain might be a noninvasive option serving as an additional gatekeeper for CAD patients with a needle-free test. Human studies are needed to validate these findings in a multicenter setting and to test whether CMR-FT can be incorporated into clinical guidelines.

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Keywords