Abstract #4864

Radiomics-Based Classification of Patients with Repaired Tetralogy of Fallot by Cardiac Magnetic Resonance

Jo-Hua Peng¹, Ming-Ting Wu², Nai-Yu Pan³, Teng-Yi Huang³, Yi-Jui Liu⁴, Ken-Pen Weng^5,6, and Hsu-Hsia Peng¹

¹Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ²Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ³Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, ⁴Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, ⁵Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ⁶Dpartment of Pediatrics, National Yang Ming Chiao Tung University, Taipei, Taiwan

Synopsis

Keywords: Heart, RadiomicsRadiomics is a novel technique of advanced cardiac magnetic resonance (CMR) phenotyping by analyzing a couple of variables of cardiac shape and tissue texture. This study aimed to develop the radiomics-based classification model to differentiate rTOF patients from normal controls and evaluate the representative features of ventricular and myocardial abnormalities in rTOF patients. In conclusion, the radiomics-based classification model can successfully differentiate rTOF patients from normal controls with routine CMR cine images. The selected features underlined the right ventricular remodeling and left ventricular myocardium fibrosis in rTOF patients.

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