Keywords: Heart, Radiomics, blood poolRadiomics features acquired from the blood pool in different chambers (LV/RV/LA/RA) at various periods within a cardiac cycle present diverse property in characterizing PH-HFpEF. Multiple blood pool radiomics features were significantly related to PCWP and mPAP (r: 0.4 – 0.643). Compared to the LV wall, the blood pools provide more efficient features (individual AUC: 0.7 – 0.821) to discriminate PH-HFpEF from controls (p < 0.05). Cine MRI-derived radiomics features of the blood pool can be used to characterize PH-HFpEF. Radiomics features of the blood pool have the potential to become novel quantitative imaging biomarkers for presenting cardiovascular pathology.
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