Keywords: Contrast Agent, Cell Tracking & Reporter GenesIn this study, gold coated microfabricated gold-coated iron particles are used for in vitro and in vivo labeling of immune cell and neural precursors, respectively for MRI. These particles have a pure iron core and protective layer of gold and exhibit extremely high magnetic moment relative to more commonly used, chemically synthesized, iron-oxide based particles. Following in situ labeling of neural precursor cells, we show that the migration of a large pool of individual cells can be visualized in time-lapse and longitudinal MRI.
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