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Abstract #4906

Sampling Time Considerations for T1 map acquisition on the 64mT Hyperfine Swoop system: A Phantom Evaluation Study

Vivian S. Nguyen1,2, Sudarshan Ragunathan3, Timothy J. Carroll4, Adil Javed5, Marcella K. Vaicik1, John G. Georgiadis1, and Keigo Kawaji1,2
1Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 2Medicine - Cardiology, University of Chicago Medical Center, Chicago, IL, United States, 3Hyperfine Inc., Guilford, CT, United States, 4Radiology, University of Chicago Medical Center, Chicago, IL, United States, 5Neurology, University of Chicago Medical Center, Chicago, IL, United States

Synopsis

Keywords: Relaxometry, Low-Field MRIT1 maps provide quantitative relaxometric measures of tissue responses that may carry correlative indices of specific disease indications. On the recently commercialized 64mT system (Hyperfine Inc.), little has been reported regarding both clinical T1 relaxometric normal values in presence of Gadolinium-based contrast and relevant acquisition schemes with Gd contrast enhancement. In this study, we examine an array of Gadolinium-doped vials that represent 10-5000 fold dilution in the vasculature using an Inversion-Recovery FSE acquisition to gain key insights on: a) anticipated normal values in presence of Gd, b) conventional fitting algorithm performance, and c) potential inferences on inversion timing selection.

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Keywords