Meeting Banner
Abstract #4935

Left DLPFC - left ACC resting state functional connectivity association with response to rTMS therapy of major depressive disorder

Pallab Bhattacharyya1, Amit Anand2, Xuemei Huang1, Mark Lowe1, and Murat Altinay1
1Cleveland Clinic Foundation, CLEVELAND, OH, United States, 2Brigham and Women's Hospital, Boston, MA, United States

Synopsis

Keywords: Psychiatric Disorders, Psychiatric DisordersHigh frequency repetitive transcranial magnetic stimulation (rTMS) targeted at left dorsolateral prefrontal cortex (lDLPFC) is an increasingly popular therapy of patients with major depressive disorder, who are inadequately responsive to medication treatment. There is evidence of resting state functional connectivity (fcMRI) between lDLPFC and left anterior cingulate cortex (lACC) playing a role in rTMS efficacy. We performed a longitudinal study by scanning patients before and after 6-week long 10-Hz rTMS therapy. Patients with lower resting state low frequency blood oxygen level dependent fluctuation correlation and anticorrelation between lDLPFC and lACC responded better to rTMS therapy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords