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Abstract #4958

Retrospective and prospective accelerated T1ρ/T2 mapping with Compressed Sensing: high resolution T1ρ mapping and simultaneous T1ρ/T2 mapping

Jeehun Kim1,2, Zhiyuan Zhang1,3, Ruiying Liu4, Brendan Eck1, Mingrui Yang1, Hongyu Li4, Mei Li1, Richard Lartey1, Carl S. Winalski1,5, Leslie Ying4,6, and Xiaojuan Li1,5
1Department of Biomedical Engineering, Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2Department of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, OH, United States, 3Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 4Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States, 5Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States, 6Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States

Synopsis

Keywords: Image Reconstruction, CartilageQuantitative MR T1rho T2 imaging shows promising results on detecting early-stage osteoarthritis, but long scan time limits the spatial resolution, making it vulnerable to partial volume averaging. Such effect reduces the sensitivity to small focal degeneration. In this study, compressed sensing reconstruction with spatio-temporal finite difference regularization was used to accelerate high-resolution (slice thickness < 2mm) T1rho imaging and standard-resolution simultaneous T1rho and T2 imaging, and evaluated the result comparing with reference imaging, retrospective and prospective reconstruction, and scan-rescan repeatability.

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