Abstract #4981

Accelerated, Free-Breathing 3D Cardiac T1ρ Mapping Pulse Sequence with XD-GRASP Reconstruction

Suvai Gunasekaran¹, KyungPyo Hong¹, Roberta Catania¹, Joshua Robinson², Rod Passman³, Aggelos Katsaggelos⁴, Cynthia Rigsby⁵, Walter Witschey⁶, and Daniel Kim¹

¹Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States, ²Cardiology, Lurie Children’s Hospital, Chicago, IL, United States, ³Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States, ⁴Electrical and Computer Engineering, Northwestern University, Evanston, IL, United States, ⁵Radiology, Lurie Children’s Hospital, Chicago, IL, United States, ⁶Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States

Synopsis

Keywords: Myocardium, Quantitative Imaging, FibrosisT1ρ mapping is an emerging non-contrast pulse sequence for measuring cardiac fibrosis. Unfortunately, current T1ρ techniques suffer from lack of coverage, poor spatial resolution, and long scan time. Thus, we developed an accelerated, free-breathing 3D cardiac T1ρ mapping pulse sequence using XD-GRASP reconstruction including both respiratory and contrast dimensions; additionally, view sharing and KWIC filtering were incorporated to improve spatial resolution. This sequence was tested in 8 patients undergoing clinically indicated cardiac MRI, resulting in robust image quality and T1ρ values that are in agreement with literature.

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