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Abstract #5006

Accelerated MRI thermometry guidance for transurethral ultrasound ablation of the prostate using locally low rank reconstruction

Ben YC Leung1, Robert M. Staruch1, and Mark Chiew2,3
1Profound Medical, Mississauga, ON, Canada, 2Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada

Synopsis

Keywords: Thermometry, Interventional Devices, TULSAMRI-guided transurethral ultrasound ablation of the prostate (TULSA) is controlled based on dynamic proton resonance frequency shift MR temperature imaging. Given the localized, but spatio-temporally coherent heating pattern, locally low rank (LLR) reconstruction could facilitate accelerated thermometry. Images acquired during TULSA in a phantom were retrospectively under-sampled by acceleration factors of R=3,4,6 by randomly sub-sampling EPI segments, and reconstructed using LLR constraints with non-overlapping 4D patches and cycle-spinning patch shifts. LLR reconstruction demonstrated lower variance than GRAPPA reconstructions in unheated regions, but increasing measurement bias at R≥4. In vivo investigation of LLR reconstruction of MR thermometry for TULSA is warranted.

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Keywords