Keywords: Diffusion/other diffusion imaging techniques, Simulations, Pseudo-diffusivityThe pseudo-diffusivity effect - arising from blood flow in capillaries - is used to characterise the diffusion-weighted MRI signal at low b-values (b<200 s/mm2) in several biophysical models. We propose here a generative model for producing vascular meshes with tunable properties - such as vessel segment radius and length, and vessel volume fraction – that are compatible with common Monte Carlo diffusion simulation frameworks. Monte Carlo simulations of pseudo-diffusivity are performed, under varying conditions, by adapting the Camino simulation toolkit to include a plug flow component to spin dynamics inside the vascular mesh; the resulting signals are validated against analytical solutions.
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