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Abstract #5025

Prospective motion correction improves gSlider accelerated diffusion imaging

Kerrin J Pine1, Luke J Edwards1, Marianna Schmidt1,2, Juliane Damm1, Fuyixue Wang3, Susie Huang3, Evgeniya Kirilina1, and Nikolaus Weiskopf1,4
1Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2Max Planck School of Cognition, Leipzig, Germany, 3A.A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, 4Felix Bloch Institute for Solid State Physics, Faculty of Physics and Earth Sciences, Leipzig University, Leipzig, Germany

Synopsis

Keywords: Diffusion/other diffusion imaging techniques, Motion Correction, DTIHigh resolution diffusion weighted imaging (DWI) is required to map cortical fibres and short association fibres in superficial white matter. The recently developed gSlider sequence allows high-resolution whole-brain DWI but is prone to motion-induced artefacts due to the long volume acquisition. We combined gSlider with prospective motion correction (PMC) using optical tracking to acquire high angular, high spatial resolution DWI. In three healthy participants, we demonstrated that PMC led to a reduction of motion artifacts, an increase of temporal SNR of around 15% and better estimates of fibre characteristics in the cortex and superficial white matter.

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